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Inhibition of Human Dyskerin as a New Approach to Target Ribosome Biogenesis
The product of the DKC1 gene, dyskerin, is required for both ribosome biogenesis and telomerase complex stabilization. Targeting these cellular processes has been explored for the development of drugs to selectively or preferentially kill cancer cells. Presently, intense research is conducted involv...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092089/ https://ncbi.nlm.nih.gov/pubmed/25010840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101971 |
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