Genome-Wide Data reveals Novel Genes for Methotrexate Response in a Large Cohort of Juvenile Idiopathic Arthritis Cases

Clinical response to methotrexate (MTX) treatment for children with juvenile idiopathic arthritis (JIA) displays considerable heterogeneity. Currently, there are no reliable predictors to identify non-responders: earlier identification could lead to targeted treatment. We genotyped 759 JIA cases fro...

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Главные авторы: Cobb, Joanna, Cule, Erika, Moncrieffe, Halima, Hinks, Anne, Ursu, Simona, Patrick, Fiona, Kassoumeri, Laura, Flynn, Edward, Bulatović, Maja, Wulffraat, Nico, van Zelst, Bertrand, de Jonge, Robert, Bohm, Marek, Dolezalova, Pavla, Hirani, Shashi, Newman, Stanton, Whitworth, Pamela, Southwood, Taunton R, De Iorio, Maria, Wedderburn, Lucy R, Thomson, Wendy
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091986/
https://ncbi.nlm.nih.gov/pubmed/24709693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.3
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