Genome-Wide Data reveals Novel Genes for Methotrexate Response in a Large Cohort of Juvenile Idiopathic Arthritis Cases

Clinical response to methotrexate (MTX) treatment for children with juvenile idiopathic arthritis (JIA) displays considerable heterogeneity. Currently, there are no reliable predictors to identify non-responders: earlier identification could lead to targeted treatment. We genotyped 759 JIA cases fro...

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Hoofdauteurs: Cobb, Joanna, Cule, Erika, Moncrieffe, Halima, Hinks, Anne, Ursu, Simona, Patrick, Fiona, Kassoumeri, Laura, Flynn, Edward, Bulatović, Maja, Wulffraat, Nico, van Zelst, Bertrand, de Jonge, Robert, Bohm, Marek, Dolezalova, Pavla, Hirani, Shashi, Newman, Stanton, Whitworth, Pamela, Southwood, Taunton R, De Iorio, Maria, Wedderburn, Lucy R, Thomson, Wendy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091986/
https://ncbi.nlm.nih.gov/pubmed/24709693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.3
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