PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin

Cantharidin is an active constituent of mylabris, a traditional Chinese medicine, and presents strong anticancer activity in various cell lines. Cantharidin is a potent and selective inhibitor of serine/threonine protein phosphatase 2A (PP2A). Our previous studies revealed the prospect of applicatio...

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Main Authors: WU, MENG-YAO, XIE, XIN, XU, ZE-KUAN, XIE, LI, CHEN, ZHENG, SHOU, LIU-MEI, GONG, FEI-RAN, XIE, YU-FENG, LI, WEI, TAO, MIN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091883/
https://ncbi.nlm.nih.gov/pubmed/24926961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3266
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