Protective Effects of 10-nitro-oleic Acid in a Hypoxia-Induced Murine Model of Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is characterized by adverse remodeling of pulmonary arteries. Although the origin of the disease and its underlying pathophysiology remain incompletely understood, inflammation has been identified as a central mediator of disease progression. Oxidative inflammat...

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Hauptverfasser: Klinke, Anna, Möller, Annika, Pekarova, Michaela, Ravekes, Thorben, Friedrichs, Kai, Berlin, Matthias, Scheu, Katrin M., Kubala, Lukas, Kolarova, Hana, Ambrozova, Gabriela, Schermuly, Ralph T., Woodcock, Steven R., Freeman, Bruce A., Rosenkranz, Stephan, Baldus, Stephan, Rudolph, Volker, Rudolph, Tanja K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091852/
https://ncbi.nlm.nih.gov/pubmed/24521348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0063OC
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