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Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation

AIM: Atrial fibrosis, one of the most striking features in the pathology of atrial fibrillation (AF), is promoted by local and systemic inflammation. Electrophilic fatty acid nitroalkenes, endogenously generated by both metabolic and inflammatory reactions, are anti-inflammatory mediators that in sy...

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Bibliographic Details
Published in:Cardiovasc Res
Main Authors: Rudolph, Tanja K., Ravekes, Thorben, Klinke, Anna, Friedrichs, Kai, Mollenhauer, Martin, Pekarova, Michaela, Ambrozova, Gabriela, Martiskova, Hana, Kaur, Jatinder-Jit, Matthes, Bianca, Schwoerer, Alex, Woodcock, Steven R., Kubala, Lukas, Freeman, Bruce A., Baldus, Stephan, Rudolph, Volker
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901131/
https://ncbi.nlm.nih.gov/pubmed/26598510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv254
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