Protective Effects of 10-nitro-oleic Acid in a Hypoxia-Induced Murine Model of Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is characterized by adverse remodeling of pulmonary arteries. Although the origin of the disease and its underlying pathophysiology remain incompletely understood, inflammation has been identified as a central mediator of disease progression. Oxidative inflammat...

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Autori principali: Klinke, Anna, Möller, Annika, Pekarova, Michaela, Ravekes, Thorben, Friedrichs, Kai, Berlin, Matthias, Scheu, Katrin M., Kubala, Lukas, Kolarova, Hana, Ambrozova, Gabriela, Schermuly, Ralph T., Woodcock, Steven R., Freeman, Bruce A., Rosenkranz, Stephan, Baldus, Stephan, Rudolph, Volker, Rudolph, Tanja K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091852/
https://ncbi.nlm.nih.gov/pubmed/24521348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0063OC
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