Intracellular lumen extension requires ERM-1-dependent apical membrane expansion and AQP-8-mediated flux

Many unicellular tubes such as capillaries form lumens intracellularly, a process that is not well understood. Here we show that the cortical membrane organizer ERM-1 is required to expand the intracellular apical/lumenal membrane and its actin undercoat during single-cell C.elegans excretory canal...

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Hlavní autoři: Khan, Liakot A., Zhang, Hongjie, Abraham, Nessy, Sun, Lei, Fleming, John T., Buechner, Matthew, Hall, David H., Gobel, Verena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091717/
https://ncbi.nlm.nih.gov/pubmed/23334498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2656
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