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Clathrin and AP-1 regulate apical polarity and lumen formation during C. elegans tubulogenesis

Clathrin coats vesicles in all eukaryotic cells and has a well-defined role in endocytosis, moving molecules away from the plasma membrane. Its function on routes towards the plasma membrane was only recently appreciated and is thought to be limited to basolateral transport. Here, an unbiased RNAi-b...

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Autors principals: Zhang, Hongjie, Kim, Ahlee, Abraham, Nessy, Khan, Liakot A., Hall, David H., Fleming, John T., Gobel, Verena
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347694/
https://ncbi.nlm.nih.gov/pubmed/22535410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077347
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