Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo

Accumulating evidence suggests that activated pancreatic stellate cells (PSC) play an important role in chronic pancreatitis (CP), and inhibition of the activated PSC is considered as a potential strategy for the treatment and prevention of CP. Herein, we disclose our findings that apigenin and its...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Haijun, Mrazek, Amy A., Wang, Xiaofu, Ding, Chunyong, Ding, Ye, Porro, Laura J., Liu, Huiling, Chao, Celia, Hellmich, Mark R., Zhou, Jia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091635/
https://ncbi.nlm.nih.gov/pubmed/24837156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.04.043
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