High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors

BACKGROUND: Recent identification of a specific role of HSF1 in cancer progression has led to new relevance of HSF1 as both a prognostic and a predictive marker. The role of HSF1 in endometrial cancer has so far been unexplored. METHODS: A total of 823 lesions from endometrial carcinoma precursors,...

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Detalhes bibliográficos
Main Authors: Engerud, H, Tangen, I L, Berg, A, Kusonmano, K, Halle, M K, Øyan, A M, Kalland, K H, Stefansson, I, Trovik, J, Salvesen, H B, Krakstad, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090731/
https://ncbi.nlm.nih.gov/pubmed/24853175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.262
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