Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity

Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. In advanced AMD, new vessels from choriocapillaris (CC) invade through the Bruch's membrane (BrM) into the retina, forming choroidal neovascularization (CNV). BrM, an elastic lamina that is located be...

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Autors principals: Sekiyama, Eiichi, Saint-Geniez, Magali, Yoneda, Kazuhito, Hisatomi, Toshio, Nakao, Shintaro, Walshe, Tony E., Maruyama, Kazuichi, Hafezi-Moghadam, Ali, Miller, Joan W., Kinoshita, Shigeru, D'Amore, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2012
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090388/
https://ncbi.nlm.nih.gov/pubmed/22067481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-184127
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