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An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris

Clinical and experimental observations indicate a role for VEGF secreted by the retinal pigment epithelium (RPE) in the maintenance of the choriocapillaris (CC). VEGF in mice is produced as three isoforms, VEGF120, VEGF164, and VEGF188, that differ in their ability to bind heparan sulfate proteoglyc...

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Detalhes bibliográficos
Main Authors: Saint-Geniez, Magali, Kurihara, Tomoki, Sekiyama, Eiichi, Maldonado, Angel E., D'Amore, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774033/
https://ncbi.nlm.nih.gov/pubmed/19841260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905010106
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