Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity

Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. In advanced AMD, new vessels from choriocapillaris (CC) invade through the Bruch's membrane (BrM) into the retina, forming choroidal neovascularization (CNV). BrM, an elastic lamina that is located be...

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Detalhes bibliográficos
Main Authors: Sekiyama, Eiichi, Saint-Geniez, Magali, Yoneda, Kazuhito, Hisatomi, Toshio, Nakao, Shintaro, Walshe, Tony E., Maruyama, Kazuichi, Hafezi-Moghadam, Ali, Miller, Joan W., Kinoshita, Shigeru, D'Amore, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2012
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090388/
https://ncbi.nlm.nih.gov/pubmed/22067481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-184127
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