α-Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons

Dendritic spines are micron-sized protrusions that constitute the primary post-synaptic sites of excitatory neurotransmission in the brain. Spines mature from a filopodia-like protrusion into a mushroom-shaped morphology with a post-synaptic density (PSD) at its tip. Modulation of the actin cytoskel...

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Main Authors: Hodges, Jennifer L., Vilchez, Samuel Martin, Asmussen, Hannelore, Whitmore, Leanna A., Horwitz, Alan Rick
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090192/
https://ncbi.nlm.nih.gov/pubmed/25007055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101770
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