ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

RhoGTPases organize the actin cytoskeleton to generate diverse polarities, from front–back polarity in migrating cells to dendritic spine morphology in neurons. For example, RhoA through its effector kinase, RhoA kinase (ROCK), activates myosin II to form actomyosin filament bundles and large adhesi...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Newell-Litwa, Karen A., Badoual, Mathilde, Asmussen, Hannelore, Patel, Heather, Whitmore, Leanna, Horwitz, Alan Rick
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508895/
https://ncbi.nlm.nih.gov/pubmed/26169356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504046
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