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Transgenic inhibition of astroglial NF-κB leads to increased axonal sparing and sprouting following spinal cord injury

We previously showed that NF-κB inactivation in astrocytes leads to improved functional recovery following spinal cord injury (SCI). This correlated with reduced expression of pro-inflammatory mediators and chondroitin sulphate proteoglycans, and increased white matter preservation. Hence we hypothe...

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Autors principals: Brambilla, Roberta, Hurtado, Andres, Persaud, Trikaldarshi, Esham, Kim, Pearse, Damien D., Oudega, Martin, Bethea, John R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090052/
https://ncbi.nlm.nih.gov/pubmed/19522780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06190.x
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