Non-steroidal Anti-Inflammatory Drugs may reduce Enterohepatic Recirculation of Mycophenolic Acid in Patients with Childhood-onset Systemic Lupus Erythematosus

BACKGROUND: The large inter-individual differences observed in mycophenolic acid (MPA) pharmacokinetics (MPA-PK) are in part attributed to large variability in enterohepatic recirculation (EHC) of the drug. MPA’s main metabolite, MPA-glucuronide is actively secreted into the bile via the multidrug r...

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Hlavní autoři: Fukuda, Tsuyoshi, Brunner, Hermine I., Sagcal-Gironella, Anna Carmela P., Vinks, Alexander A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090025/
https://ncbi.nlm.nih.gov/pubmed/21860343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e318228195f
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