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Non-steroidal Anti-Inflammatory Drugs may reduce Enterohepatic Recirculation of Mycophenolic Acid in Patients with Childhood-onset Systemic Lupus Erythematosus
BACKGROUND: The large inter-individual differences observed in mycophenolic acid (MPA) pharmacokinetics (MPA-PK) are in part attributed to large variability in enterohepatic recirculation (EHC) of the drug. MPA’s main metabolite, MPA-glucuronide is actively secreted into the bile via the multidrug r...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090025/ https://ncbi.nlm.nih.gov/pubmed/21860343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e318228195f |
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