Development of population PK model with enterohepatic circulation for mycophenolic acid in patients with childhood-onset systemic lupus erythematosus

AIM: This study aimed to develop a population pharmacokinetic (PK) enterohepatic recycling model for MPA in patients with childhood-onset systemic lupus erythematosus (cSLE). METHODS: MPA concentration–time data were from outpatients on stable oral mycophenolate mofetil (MMF) and collected under fas...

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Detalhes bibliográficos
Main Authors: Sherwin, Catherine M T, Sagcal-Gironella, Anna Carmela P, Fukuda, Tsuyoshi, Brunner, Hermine I, Vinks, Alexander A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403200/
https://ncbi.nlm.nih.gov/pubmed/22053944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04140.x
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