Optimization of High Grade Glioma Cell Culture from Surgical Specimens for Use in Clinically Relevant Animal Models and 3D Immunochemistry

Glioblastomas, the most common and aggressive form of astrocytoma, are refractory to therapy, and molecularly heterogeneous. The ability to establish cell cultures that preserve the genomic profile of the parental tumors, for use in patient specific in vitro and in vivo models, has the potential to...

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Main Authors: Hasselbach, Laura A., Irtenkauf, Susan M., Lemke, Nancy W., Nelson, Kevin K., Berezovsky, Artem D., Carlton, Enoch T., Transou, Andrea D., Mikkelsen, Tom, deCarvalho, Ana C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2014
Ábhair:
Medicine
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089397/
https://ncbi.nlm.nih.gov/pubmed/24429465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51088
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