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Structural evolution and membrane interactions of Alzheimer's amyloid-beta peptide oligomers: New knowledge from single-molecule fluorescence studies

Amyloid-β peptide (Aβ) oligomers may represent the proximal neurotoxin in Alzheimer's disease. Single-molecule microscopy (SMM) techniques have recently emerged as a method for overcoming the innate difficulties of working with amyloid-β, including the peptide's low endogenous concentratio...

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Библиографические подробности
Главные авторы: Johnson, Robin D, Steel, Duncan G, Gafni, Ari
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088971/
https://ncbi.nlm.nih.gov/pubmed/24753305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2479
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