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Gene therapy that inhibits NF-κB results in apoptosis of human hepatocarcinoma by recombinant adenovirus

AIM: To investigate whether the recombinant adenovirus induces the TNF-α-mediated apoptosis in vivo. METHODS: Human hepatocarcinoma cell line (HepG(2)) cells were transfected into BALB/c nude mice, and the tumor growth curve was drawn. We analyzed apoptosis in HepG(2) cells by TUNEL, HE staining and...

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Autori principali: Li, Tie-Jun, Jia, Li-Ping, Gao, Xiao-Ling, Huang, Ai-Long
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Co., Limited 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088193/
https://ncbi.nlm.nih.gov/pubmed/16981256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i33.5287
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