Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells

Regulations between NF-κB and HIF-1 have not been adequately addressed in previous research. Here, we report that hypoxia increased NF-κB in hepatocellular carcinoma cells. The HIF-1 protein level was rapidly induced by protein stabilization (by 2 hours) and then moderately decreased, whereas mRNA l...

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Опубликовано в: :Oncotarget
Главные авторы: Jiang, Yuan, Zhu, Ying, Wang, Xinxin, Gong, Juan, Hu, Chunyan, Guo, Bo, Zhu, Bo, Li, Yongsheng
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496226/
https://ncbi.nlm.nih.gov/pubmed/25823824
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