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A novel signaling pathway regulates colon cancer angiogenesis through Norrin

Norrin binds to the frizzled-4 receptor, stimulating canonical Wnt signaling. We investigate here the role of colorectal cancer (CRC) produced Norrin in endothelial cell growth, motility, and blood vessel formation, as well as the expression of the Norrin signaling pathway components in the CRC tumo...

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Detaylı Bibliyografya
Asıl Yazarlar: Planutis, Kestutis, Planutiene, Marina, Holcombe, Randall F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088094/
https://ncbi.nlm.nih.gov/pubmed/25005225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05630
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