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A novel signaling pathway regulates colon cancer angiogenesis through Norrin

Norrin binds to the frizzled-4 receptor, stimulating canonical Wnt signaling. We investigate here the role of colorectal cancer (CRC) produced Norrin in endothelial cell growth, motility, and blood vessel formation, as well as the expression of the Norrin signaling pathway components in the CRC tumo...

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Hlavní autoři: Planutis, Kestutis, Planutiene, Marina, Holcombe, Randall F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088094/
https://ncbi.nlm.nih.gov/pubmed/25005225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05630
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