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A novel signaling pathway regulates colon cancer angiogenesis through Norrin
Norrin binds to the frizzled-4 receptor, stimulating canonical Wnt signaling. We investigate here the role of colorectal cancer (CRC) produced Norrin in endothelial cell growth, motility, and blood vessel formation, as well as the expression of the Norrin signaling pathway components in the CRC tumo...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4088094/ https://ncbi.nlm.nih.gov/pubmed/25005225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05630 |
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