Reversing multidrug resistance by RNA interference through the suppression of MDR1 gene in human hepatoma cells

AIM: To reverse the multidrug resistance (MDR) by RNA interference (RNAi)-mediated MDR1 suppression in hepatoma cells. METHODS: For reversing MDR by RNAi technology, two different short hairpin RNAs (shRNAs) were designed and constructed into pGenSil-1 plasmid, respectively. They were then transfect...

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Detalhes bibliográficos
Main Authors: Chen, Xiao-Ping, Wang, Qi, Guan, Jian, Huang, Zhi-Yong, Zhang, Wan-Guang, Zhang, Bi-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Liver Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087887/
https://ncbi.nlm.nih.gov/pubmed/16733848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i21.3332
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