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Down-regulation of survivin expression by small interfering RNA induces pancreatic cancer cell apoptosis and enhances its radiosensitivity

AIM: To investigate the inhibitory effect of small interfering RNA (siRNA) on the expression of survivin in pancreatic cancer cell line PC-2 and the role of siRNA in inducing PC-2 cell apoptosis and enhancing its radiosensitivity. METHODS: A siRNA plasmid expression vector against survivin was const...

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Detalhes bibliográficos
Main Authors: Guan, Hai-Tao, Xue, Xing-Huan, Dai, Zhi-Jun, Wang, Xi-Jing, Li, Ang, Qin, Zhao-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087808/
https://ncbi.nlm.nih.gov/pubmed/16718816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i18.2901
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