State-Dependent Network Connectivity Determines Gating in a K(+) Channel

X-ray crystallography has provided tremendous insight into the different structural states of membrane proteins and, in particular, of ion channels. However, the molecular forces that determine the thermodynamic stability of a particular state are poorly understood. Here we analyze the different X-r...

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Autores principales: Bollepalli, Murali K., Fowler, Philip W., Rapedius, Markus, Shang, Lijun, Sansom, Mark S.P., Tucker, Stephen J., Baukrowitz, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087272/
https://ncbi.nlm.nih.gov/pubmed/24980796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.04.018
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