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The canonical α-defensin salt-bridge facilitates folding and confers proteolytic resistance by induction of backbone stability in mouse cryptdin-4
Salt-bridge interactions between acidic and basic amino acids contribute to the structural stability of proteins and to protein-protein interactions. A conserved salt-bridge is a canonical feature of the α-defensin antimicrobial peptide family, but the role of this common structural element has not...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086743/ https://ncbi.nlm.nih.gov/pubmed/22286872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-012-1220-3 |
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