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The canonical α-defensin salt-bridge facilitates folding and confers proteolytic resistance by induction of backbone stability in mouse cryptdin-4

Salt-bridge interactions between acidic and basic amino acids contribute to the structural stability of proteins and to protein-protein interactions. A conserved salt-bridge is a canonical feature of the α-defensin antimicrobial peptide family, but the role of this common structural element has not...

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Bibliografske podrobnosti
Main Authors: Andersson, Håkan S., Figueredo, Sharel M., Haugaard-Kedström, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, André J., Rosengren, K. Johan
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086743/
https://ncbi.nlm.nih.gov/pubmed/22286872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-012-1220-3
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