Φορτώνει......
Inhibition of bactericidal activity is maintained in a mouse α-defensin precursor with proregion truncations
α-Defensin biosynthesis requires the proteolytic conversion of inactive precursors to microbicidal forms. In mouse Paneth cell pro-α-defensin proCrp4((20–92)), anionic amino acids positioned near the proregion N-terminus inhibit proCrp4 activity by an apparent charge neutralization mechanism. Becaus...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814988/ https://ncbi.nlm.nih.gov/pubmed/19837119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.10.004 |
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