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Severity of drinking as a predictor of efficacy of the combination of ondansetron and topiramate in rat models of ethanol consumption and relapse
RATIONALE: Alcohol dependence is the third leading cause of preventable death in the USA. While single-agent pharmacotherapies have variable efficacy, medication combinations may produce additive effects by modulating multiple neural pathways. OBJECTIVES: Here, we examined in animal models of ethano...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086466/ https://ncbi.nlm.nih.gov/pubmed/21424693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2253-0 |
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