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The efficacy of a low dose combination of topiramate and naltrexone on ethanol reinforcement and consumption in rat models

RATIONALE: Combined medication approaches, by targeting multiple neurotransmitter systems involved in alcohol use disorders (AUDs), may be more efficacious than single-medication approaches. OBJECTIVES: We examined, in animals models of consumption and reinforcement, the combined effects of naltrexo...

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Detalhes bibliográficos
Main Authors: Moore, Catherine F, Protzuk, Omar A, Johnson, Bankole A, Lynch, Wendy J
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886549/
https://ncbi.nlm.nih.gov/pubmed/24252444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2013.11.013
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