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TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes

TRPM1(melastatin), which encodes the founding member of the TRPM family of transient receptor potential (TRP) ion channels, was first identified by its reduced expression in a highly metastatic mouse melanoma cell line. Clinically, TRPM1 is used as a predictor of melanoma progression in humans becau...

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Main Authors: Oancea, Elena, Vriens, Joris, Brauchi, Sebastian, Jun, Janice, Splawski, Igor, Clapham, David E.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086358/
https://ncbi.nlm.nih.gov/pubmed/19436059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000146
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