Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

Mutations in TRPM1, a calcium channel expressed in retinal bipolar cells and epidermal melanocytes, cause complete congenital stationary night blindness with no discernible skin phenotype. In the retina, TRPM1 activity is negatively coupled to metabotropic glutamate receptor 6 (mGluR6) signaling thr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Devi, Sulochana, Markandeya, Yogananda, Maddodi, Nityanand, Dhingra, Anuradha, Vardi, Noga, Balijepalli, Ravi C, Setaluri, Vijayasaradhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682403/
https://ncbi.nlm.nih.gov/pubmed/23452348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12083
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge