Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

Mutations in TRPM1, a calcium channel expressed in retinal bipolar cells and epidermal melanocytes, cause complete congenital stationary night blindness with no discernible skin phenotype. In the retina, TRPM1 activity is negatively coupled to metabotropic glutamate receptor 6 (mGluR6) signaling thr...

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Hlavní autoři: Devi, Sulochana, Markandeya, Yogananda, Maddodi, Nityanand, Dhingra, Anuradha, Vardi, Noga, Balijepalli, Ravi C, Setaluri, Vijayasaradhi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682403/
https://ncbi.nlm.nih.gov/pubmed/23452348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12083
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