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High CYP2A6 Enzyme Activity as Measured by a Caffeine Test and Unique Distribution of CYP2A6 Variant Alleles in Ethiopian Population

CYP2A6 metabolizes clinically relevant drugs, including antiretroviral and antimalarial drugs of major public health importance for the African populations. CYP2A6 genotype–phenotype relationship in African populations, and implications of geographic differences on enzyme activity, remain to be inve...

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Detalhes bibliográficos
Main Authors: Aklillu, Eleni, Djordjevic, Natasa, Carrillo, Juan Antonio, Makonnen, Eyasu, Bertilsson, Leif, Ingelman-Sundberg, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086241/
https://ncbi.nlm.nih.gov/pubmed/24380444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2013.0140
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