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The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice

Polymorphic rhoptry secreted kinases (ROPs) are essential virulence factors of Toxoplasma gondii. In particular, the pseudokinase ROP5 is the major determinant of acute virulence in mice, but the underlying mechanisms are unclear. We developed a tandem affinity protein tagging and purification appro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Etheridge, Ronald D., Alaganan, Aditi, Tang, Keliang, Lou, Hua Jane, Turk, Benjamin E., Sibley, L. David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086214/
https://ncbi.nlm.nih.gov/pubmed/24832449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.04.002
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