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Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

The population structure of Toxoplasma gondii includes three highly prevalent clonal lineages referred to as types I, II, and III, which differ greatly in virulence in the mouse model. Previous studies have implicated a family of serine/threonine protein kinases found in rhoptries (ROPs) as importan...

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Detalhes bibliográficos
Main Authors: Behnke, Michael S., Khan, Asis, Wootton, John C., Dubey, Jitender P., Tang, Keliang, Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111276/
https://ncbi.nlm.nih.gov/pubmed/21586633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015338108
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