Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse

The intracellular parasite Toxoplasma gondii enjoys a wide host range and is adept at surviving in both naive and activated macrophages. Previous studies have emphasized the importance of the active serine-threonine protein kinase rhoptry protein 18 (ROP18), which targets immunity-related GTPases (I...

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Bibliographic Details
Main Authors: Alaganan, Aditi, Fentress, Sarah J., Tang, Keliang, Wang, Qiuling, Sibley, L. David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903209/
https://ncbi.nlm.nih.gov/pubmed/24390541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313501111
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