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Mutations in Igα (CD79a) result in a complete block in B-cell development

Mutations in Btk, μ heavy chain, or the surrogate light chain account for 85–90% of patients with early onset hypogammaglobulinemia and absent B cells. The nature of the defect in the remaining patients is unknown. We screened 25 such patients for mutations in genes encoding components of the pre–B-...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Minegishi, Yoshiyuki, Coustan-Smith, Elaine, Rapalus, Lisa, Ersoy, Fügen, Campana, Dario, Conley, Mary Ellen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 1999
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC408581/
https://ncbi.nlm.nih.gov/pubmed/10525050
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