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Relevance of G-quadruplex structures to pharmacogenetics

G-quadruplexes are non-canonical secondary structures formed within nucleic acids that are involved in modulating cellular processes such as replication, gene regulation, recombination and epigenetics. Within genes, there is mounting evidence of G-quadruplex involvement in transcriptional and post t...

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Detalhes bibliográficos
Main Authors: Cree, Simone L., Kennedy, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085647/
https://ncbi.nlm.nih.gov/pubmed/25071578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00160
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