Yüklüyor......

G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter.

We observed apparent non-Mendelian behaviour of alleles when genotyping a region in a CpG island at the 5' end of the maternally imprinted human MEST isoform. This region contains three single nucleotide polymorphisms (SNPs) in total linkage disequilibrium, such that only two haplotypes occur i...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Aaron J Stevens, Selma Stuffrein-Roberts, Simone L Cree, Andrew Gibb, Allison L Miller, Kit Doudney, Alan Aitchison, Michael R Eccles, Peter R Joyce, Vyacheslav V Filichev, Martin A Kennedy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2014-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC4249981?pdf=render
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!