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Functional analysis of the acetylation of human p53 in DNA damage responses

As a critical tumor suppressor, p53 is inactivated in human cancer cells by somatic gene mutation or disruption of pathways required for its activation. Therefore, it is critical to elucidate the mechanism underlying p53 activation after genotoxic and cellular stresses. Accumulating evidence has ind...

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Detalhes bibliográficos
Main Authors: Chung, Sun-Ku, Zhu, Shengyun, Xu, Yang, Fu, Xuemei
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085286/
https://ncbi.nlm.nih.gov/pubmed/24691905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0048-x
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