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Free-Energy Landscape of Reverse tRNA Translocation through the Ribosome Analyzed by Electron Microscopy Density Maps and Molecular Dynamics Simulations

To understand the mechanism of reverse tRNA translocation in the ribosome, all-atom molecular dynamics simulations of the ribosome-tRNAs-mRNA-EFG complex were performed. The complex at the post-translocational state was directed towards the translocational and pre-translocational states by fitting t...

詳細記述

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書誌詳細
主要な著者: Ishida, Hisashi, Matsumoto, Atsushi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084982/
https://ncbi.nlm.nih.gov/pubmed/24999999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101951
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