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Reverse Translocation of tRNA in the Ribosome

A widely held view is that directional movement of tRNA in the ribosome is determined by an intrinsic mechanism and driven thermodynamically by transpeptidation. Here, we show that, in certain ribosomal complexes, the pretranslocation (PRE) state is thermodynamically favored over the posttranslocati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shoji, Shinichiro, Walker, Sarah E., Fredrick, Kurt
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661759/
https://ncbi.nlm.nih.gov/pubmed/17189194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.11.025
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