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Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome

Functional rearrangements in biomolecular assemblies result from diffusion across an underlying energy landscape. While bulk kinetic measurements rely on discrete state-like approximations to the energy landscape, single-molecule methods can project the free energy onto specific coordinates. With me...

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書目詳細資料
Main Authors: Whitford, Paul C., Blanchard, Scott C., Cate, Jamie H. D., Sanbonmatsu, Karissa Y.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605090/
https://ncbi.nlm.nih.gov/pubmed/23555233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003003
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