Accommodation of aminoacyl-tRNA into the ribosome involves reversible excursions along multiple pathways

The ribosome is a massive ribonucleoprotein complex (∼2.4 MDa) that utilizes large-scale structural fluctuations to produce unidirectional protein synthesis. Accommodation is a key conformational change during transfer RNA (tRNA) selection that allows movement of tRNA into the ribosome. Here, we add...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Whitford, Paul C., Geggier, Peter, Altman, Roger B., Blanchard, Scott C., Onuchic, José N., Sanbonmatsu, Karissa Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874171/
https://ncbi.nlm.nih.gov/pubmed/20427512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2035410
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