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Accommodation of aminoacyl-tRNA into the ribosome involves reversible excursions along multiple pathways
The ribosome is a massive ribonucleoprotein complex (∼2.4 MDa) that utilizes large-scale structural fluctuations to produce unidirectional protein synthesis. Accommodation is a key conformational change during transfer RNA (tRNA) selection that allows movement of tRNA into the ribosome. Here, we add...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874171/ https://ncbi.nlm.nih.gov/pubmed/20427512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2035410 |
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