Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome

Aminoacyl-tRNA (aa-tRNA), in a ternary complex with Elongation Factor-Tu (EF-Tu) and GTP, enters the aminoacyl (A) site of the ribosome via a multi-step, mRNA codon-dependent mechanism. This process gives rise to the preferential selection of cognate aa-tRNAs for each mRNA codon and consequently the...

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Main Authors: Geggier, Peter, Dave, Richa, Feldman, Michael B., Terry, Daniel S., Altman, Roger B., Munro, James B., Blanchard, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917329/
https://ncbi.nlm.nih.gov/pubmed/20434456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.038
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